Pantoprazole davis pdf8/30/2023 ![]() Patients should not take sertraline with other drugs that increase serotonin levels (e.g., MAO inhibitors).īe alert for increased depression and suicidal thoughts and ideology, especially when initiating drug treatment, and in children and teenagers. Monitor and report signs of serotonin syndrome, including hyperthermia, rigidity, myoclonus, and autonomic instability with fluctuating vital signs and extreme agitation that may proceed to delirium and coma. Report these signs to the physician immediately. Symptoms typically occur within 4–14 days after initiation of drug therapy but can occur at any time during drug use. Watch for signs of neuroleptic malignant syndrome, including hyperthermia, diaphoresis, generalized muscle rigidity, altered mental status, tachycardia, changes in blood pressure (BP), and incontinence.
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